Research Interests

My overarching interest is in how proteins are regulated, and in particular that they are not simply turned on or off by single signals, but are modulated in response to multiple inputs to meet the needs of the cell at the time. In my work, I am studying how different signals, such as post-translational modifications, ligands, and association with other biological macromolecules including DNA, change the structure and dynamics of proteins of the glucocorticoid receptor, a steroid activated transcription factor that is one of the primary targets in the treatment of leukemias and lymphomas.

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Events

Biology Seminar: "Evolution of Staphylococcus aureus in chronic lung infections" promotional image

Biology Seminar: "Evolution of Staphylococcus aureus in chronic lung infections"

Friday, October 23, 2026 3:30pm
Biology Building East
The Department of Biology’s seminar speaker on Friday, October 23, is Anthony Fischer, MD, PhD, Clinical Associate Professor of Pediatrics - Pulmonary Medicine, in the Stead Family Department of Pediatrics at the University of Iowa. His seminar will be held at 3:30pm in Kollros Auditorium (Room 101), Biology Building East (BBE).

BMB Research Workshop

Tuesday, October 27, 2026 12:30pm to 1:20pm
Medical Education Research Facility

The Department of Biochemistry and Molecular Biology holds research workshops featuring internal speakers on Tuesdays, 12:30-1:20pm. For Fall 2026, these will occur in 1117 MERF. Presentation titles are not publicly available due to the use of unpublished research. Individuals interested in attending workshops or being added to the email list should contact the office at biochem@uiowa.edu.

Aug. 25: CANCELED

Sept. 1: CANCELED

Sept. 8: RESERVED

Sept. 15: Steve Guzman, PhD, Postdoc Fellow, Biomedical...

Biochemistry Seminar: "Structural Mechanisms of DNA Replication Restart in Bacteria" promotional image

Biochemistry Seminar: "Structural Mechanisms of DNA Replication Restart in Bacteria"

Thursday, October 29, 2026 10:30am to 11:20am
Medical Education Research Facility

"Structural Mechanisms of DNA Replication Restart in Bacteria"

Presented by

James Keck, Ph.D.
Professor of Biomolecular Chemistry
University of Wisconsin-Madison

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